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Antibodies

Anti-CD88 / C5aR Monoclonal Antibody (Clone:S5/1)Purified

Product Sizes
0.1 mg
£532.00
30-1531-0.1MG
About this Product
SKU:
30-1531
Additional Names:
C5AR1||C5AR||C5R1
translate.label.attr.clone:
S5/1
Clonality:
Monoclonal
Extra Details:
CD88 / C5aR is a G protein-coupled seven membrane-spanning protein serving as a receptor for C5a component of the complement cascade; and is expressed mainly by monocytes; macrophages; neutrophils; eosinophils; and mast cells; but also e.g. by hepatocytes; glial cells; vascular endothelial cells; or cardiomyocytes. The binding of C5a to CD88 is associated with inflammatory response; including superoxide anion production; chemotaxis; and increased production of acute phase proteins. Expression of CD88 on synovial mast cells and their C5a-mediated degranulation plays a role in pathogenesis of rheumatoid arthritis.
Format:
Purified
Host:
Mouse
Immunogen:
Recombinant N-terminal peptide (Asp15-Asp27) of human C5aR
Isotype:
Mouse IgG2a
Purification:
Purified by protein-A affinity chromatography
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 2-8[o]C. Do not freeze.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
Figure 2: Separation of human neutrophil granulocytes (red-filled) from lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD88 (S5/1) purified antibody (GAM APC).
Figure 2: Separation of human neutrophil granulocytes (red-filled) from lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD88 (S5/1) purified antibody (GAM APC).