FITC Conjugated Anti-CD79a Monoclonal Antibody (Clone:HM47)
Product Sizes
100 Tests
£581.00
30-1528F-100TESTS
About this Product
- SKU:
- 30-1528F
- Additional Names:
- CD79A||IGA||MB1
- translate.label.attr.clone:
- HM47
- Clonality:
- Monoclonal
- Conjugate:
- FITC
- Extra Details:
- CD79a (Ig alpha; MB1) forms disulfide-linked heterodimer with CD79b (Ig beta). They both are transmembrane proteins with extended cytoplasmic domains containing immunoreceptor tyrosine activation motives (ITAMs); and together with cell surface immunoglobulin they constitute B-cell antigen-specific receptor (BCR). CD79a and b are the first components of BCR that are expressed developmentally. They appear on pro-B cells in association with the endoplasmic reticulum chaperone calnexin. Subsequently; in pre-B cells; CD79 heterodimer is associated with lambda5-VpreB surrogate immunoglobulin and later with antigen-specific surface immunoglobulins. At the plasma cell stage; CD79a is present as an intracellular component. CD79a/b complex interacts with Src-family tyrosine kinase Lyn; which phosphorylates its cytoplasmic ITAM motives to form docking sites for downstream signaling.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Synthetic peptide corresponding to C terminal amino acids 208-222 of human CD79a
- Isotype:
- Mouse IgG1
- Purification:
- Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C protected from light. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:30-1528F 1.jpeg
