Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout

APC Conjugated Anti-DLL4 (Clone : MHD4-46)

Product Sizes
0.1 mg
£649.00
30-1517AC-0.1MG
About this Product
SKU:
30-1517AC
Additional Names:
Delta like ligand 4; AOS6; canonical Notch ligand 4;delta like canonical Notch ligand 4
translate.label.attr.clone:
MHD4-46
Clonality:
Monoclonal
Conjugate:
APC
Extra Details:
DLL4 (Delta-like 4) is one of five ligands of Notch receptors. It interacts with Notch1 and Notch4. DLL4 is up-regulated at sites of physiologic and pathologic angiogenesis; whereas its expression is low in most adult normal tissues. It is also highly expressed in human clear-cell renal carcinomas; bladder cancers; and breast cancers. Blocking the DLL4-Notch interaction seems to be a promissing therapeutic approach. Specificity : The mouse monoclonal antibody MHD4-46 recognizes the extracellular domain of DLL4 (Delta-like ligand 4); a type I transmembrane protein which plays an important role in vascular development.
Immunogen:
recombinant soluble human DLL4
Isotype:
Mouse IgG1 kappa
Purification:
Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules:Conjugated Protein
Figure 1 : Separation of DLL4 transfected CHO cells stained using anti-DLL4 (MHD4-46) APC antibody (concentration in sample 5 μg/ml; red-filled) from DLL4 transfected CHO cells stained using mouse IgG1 isotype control (MOPC-21) APC antibody (concentration in sample 5 μg/ml; same as DLL4 APC antibody concentration; black-dashed) in flow cytometry analysis (surface staining).