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Antibodies

Anti-CD195 / CCR5 Monoclonal Antibody (Clone:T21/8) Biotin Conjugated

Product Sizes
0.1 mg
£581.00
30-1509-B-0.1MG
About this Product
SKU:
30-1509-B
Additional Names:
CCR5||CMKBR5
translate.label.attr.clone:
T21/8
Clonality:
Monoclonal
Conjugate:
Biotin
Extra Details:
Specificity: The mouse monoclonal antibody T21/8 recognizes an extracellular epitope on the N-teminus of CD195; an approximately 45 kDa G-protein coupled receptor 1 family protein expressed on resting T cells; monocytes; macrophages; and immature dendritic cells. Description: CD195 / CCR5 (also known as CKR-5) is a receptor for inflammatory CC-chemokines (characterized by a pair of adjacent cysteine residues); such as MIP-1 alpha; MIP-1 beta; or RANTES. It is a G protein-associated seven-pass transmembrane protein expressed on resting T cells with memory/effector phenotype; monocytes; macrophages and immature dendritic cells. This chemokine receptor regulates the activation and directed migration of leukocytes. Importantly; along with CD4; CD195 / CCR5 functions as a major receptor for HIV. Their ligand is the viral glycoprotein gp120.
Host:
Mouse
Immunogen:
CCR5 peptide (Met1-Lys22) KLH conjugate
Isotype:
Mouse IgG1 kappa
Purification:
Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 2-8[o]C. Do not freeze.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
Figure 2: Separation of human monocytes (red-filled) from lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD195 (T21/8) biotin antibody (concentration in sample 5μg/ml; Streptavidin APC).
Figure 2: Separation of human monocytes (red-filled) from lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD195 (T21/8) biotin antibody (concentration in sample 5μg/ml; Streptavidin APC).