Anti-SCIMP Monoclonal Antibody (Clone:NVL-07)
Product Sizes
0.1 mg
£581.00
30-1506-0.1MG
About this Product
- SKU:
- 30-1506
- Additional Names:
- SCIMP||C17orf87||UNQ5783/PRO16090
- translate.label.attr.clone:
- NVL-07
- Clonality:
- Monoclonal
- Extra Details:
- SCIMP (SLP adaptor and Csk interacting membrane protein); also known as Nvl; is a palmitoylated transmembrane adaptor protein expressed in professional antigen presenting cells; most prominently in the lymph nodes and spleen. It is associated with tetraspanin-enriched microdomains (together with MHC II). There is a close relationship between SCIMP and tyrosinkinase Lyn; which is constitutively bound to it by its SH3 domain. After MHC II-mediated stimulation in the immunological synapse SCIMP becomes phosphorylated at several tyrosine residues and provides docking sites for Grb2 and SLP65 or SLP76 adaptors transducing the signal downstream; as well as for the kinase Csk with modulatory roles.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Recombinant intracellular part of human SCIMP
- Isotype:
- Mouse IgG2a
- Purification:
- Purified by protein-A affinity chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
