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Antibodies

Anti-FOLR2 Monoclonal Antibody (Clone:EM-35)

Product Sizes
0.1 mg
£532.00
30-1498-0.1MG
About this Product
SKU:
30-1498
Additional Names:
FOLR2
translate.label.attr.clone:
EM-35
Clonality:
Monoclonal
Extra Details:
FOLR2 (folate receptor beta) is a cell surface protein that was originally thought to be specific for placenta; but it can be also expressed in other tissues; including hematopoietic cells. Its expression is increased in malignant tissues. FOLR2 may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. FOLR2 is a marker for macrophages generated in the presence of M-CSF (M2); including M2-like tumor-associated macrophages; which exert potent immunosuppressive functions within the tumor environment; but not GM-CSF (M1); and whose expression correlates with increased folate uptake ability.
Format:
Purified
Host:
Mouse
Immunogen:
BW5147alpha;beta- cells
Isotype:
Mouse IgG1
Purification:
Purified by protein-A affinity chromatography
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 2-8[o]C. Do not freeze.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody