Anti-Drebrin Monoclonal Antibody (Clone:DBN-N-03)
Product Sizes
0.1 mg
£581.00
30-1496-0.1MG
About this Product
- SKU:
- 30-1496
- Additional Names:
- Developmentally-regulated brain protein
- translate.label.attr.clone:
- DBN-N-03
- Clonality:
- Monoclonal
- Extra Details:
- Drebrin is an actin-binding protein; which is expressed mainly in neurons and plays important role in their morphogenesis. The highest level of its expression is in developing brain. Both in neurons and non-neuronal cells drebrin acts as a key regulator of actin cytoskeleton remodelling; affecting especially intercellular junctions; such as dendritic spines of neurons or the immune synapses of T cells. Decrease of drebrin amount in the brain seems to be associated with Alzheimer's disease and Down syndrome; and in case of B-cell precursor acute lymphoblastic leukemia (BCP-ALL) lower drebrin expression correlates with higher risk of relapse.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Bacterially expressed N-terminal fragment of recombinant human drebrin (aa 1-326)
- Isotype:
- Mouse IgG2b
- Purification:
- Purified by protein-A affinity chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
