Anti-Granzyme B Monoclonal Antibody (Clone:CLB-GB11)
Product Sizes
0.1 mg
£570.00
30-1444-0.1MG
About this Product
- SKU:
- 30-1444
- Additional Names:
- GZMB||CGL1||CSPB||CTLA1||GRB
- translate.label.attr.clone:
- CLB-GB11
- Clonality:
- Monoclonal
- Extra Details:
- Granzyme B is a serine protease that is expressed in cytoplasmic granules of cytotoxic T lymphocytes and NK cells. Vectorial secretion of perforin and granzymes is responsible for their granule-mediated cytotoxicity. Granzyme B plays a pivotal role in the induction of apoptosis in the target cells by activation of caspases. Moreover; granzyme B was reported to cleave directly alpha-tubulin; leading to perturbation of microtubule networks during the induced cell death.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Human NK cell line YT-INDY-derived granzyme B
- Isotype:
- Mouse IgG1
- Purification:
- Purified by protein-A affinity chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
