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Antibodies

Anti-CD80 Monoclonal Antibody (Clone:16-10A1)

Product Sizes
0.1 mg
£489.00
30-1438-0.1MG
About this Product
SKU:
30-1438
translate.label.attr.clone:
16-10A1
Clonality:
Monoclonal
Extra Details:
CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CTLA-4 (CD152). The both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation; the both molecules can also substitute for each other in this process. The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet; there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response.
Format:
Purified
Host:
Hamster
Immunogen:
CD80-transfected CHO cell line
Isotype:
Hamster IgG2
Purification:
Purified by protein-A affinity chromatography
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 2-8[o]C. Do not freeze.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
Figure 1: FLOW analysis of Balb C mouse splenocytes stimulated with LPS (3 days) stained with purified CD80 (clone 16-10A1; red) or Armenian hamster IgG isotype control (green); followed by goat anti-Armenian hamster IgG PE.