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Antibodies

Anti-CD106 / VCAM-1 Monoclonal Antibody (Clone:STA)

Product Sizes
0.1 mg
£532.00
30-1424-0.1MG
About this Product
SKU:
30-1424
Additional Names:
VCAM1
translate.label.attr.clone:
STA
Clonality:
Monoclonal
Extra Details:
CD106 / VCAM-1 (vascular cell adhesion molecule-1) is an Ig-like cell surface adhesion molecule binding VLA-4 integrin. VCAM-1 is a potent T cell costimulatory molecule taking part in their positive selection and survival; as well as in adhesion; transendothelial migration and activation of peripheral T cells. VCAM-1 is also involved in endothelial cell-cell contacts. Whereas VCAM-1 normally mediates leukocyte extravasion to sites of tissue inflammation; tumour cells can use overexpressed VCAM-1 to escape T cell immunity. Soluble form of VCAM-1 (sVCAM-1) is an inflammatory marker and can be used also in prognosis of subsequent cariovascular events following acute coronary syndromes.
Format:
Purified
Host:
Mouse
Immunogen:
Human DS6 T cell line
Isotype:
Mouse IgG1
Purification:
Purified by protein-A affinity chromatography
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 2-8[o]C. Do not freeze.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody