Anti-H-Ras Monoclonal Antibody (Clone:H-RAS-03)
Product Sizes
0.1 mg
£551.00
30-1365-0.1MG
About this Product
- SKU:
- 30-1365
- Additional Names:
- HRAS||HRAS1
- translate.label.attr.clone:
- H-RAS-03
- Clonality:
- Monoclonal
- Extra Details:
- H-Ras is one of three ubiquitously isoforms of Ras GTPase that operate at the intracellular leaflet of the plasma membrane to regulate multiple signal transduction pathways; such as mitogen-activated protein kinase (MAPK) cascade. H Ras is anchored to the plasma membrane by farnesyl and two palmityl residues. GTP loading decreases H-Ras affinity for lipid rafts and allows the protein to target to nonraft microdomains; the primary sites of H-Ras signaling. Sos protein and other guanine nucleotide-exchange factors catalyze dissociation of GDP from Ras. Besides its roles in the plasma membrane; active H-Ras also diffuses through the cytoplasm on nanoparticles termed rasosomes; which is dependent on Ras palmitoylation.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Peptide corresponding to amino acids DIHQYREQIKRVKDSDDC of human H-Ras protein
- Isotype:
- Mouse IgG1
- Purification:
- Purified by protein-A affinity chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
