Anti-SHIP-1 Monoclonal Antibody (Clone:SHIP-01)
Product Sizes
0.1 mg
£551.00
30-1362-0.1MG
About this Product
- SKU:
- 30-1362
- Additional Names:
- INPP5D||SHIP||SHIP1
- translate.label.attr.clone:
- SHIP-01
- Clonality:
- Monoclonal
- Extra Details:
- SHIP-1 (SH2 domain containing inositol phosphatase-1) is a 5´inositol phosphatase that regulates cell responses in lymphocytes and myeloid cells by hydrolyzing the second messenger PI(3;4;5) trisphosphate. SHIP-1 is recruited upon engagement of both inhibitory and activatory receptors; such as FcgammaRIIB; Fcgamma RIII; FcepsilonRI or cytokine and growth factor receptors; and supresses PI3K-dependent signaling; down-regulates cell migration and invasion of transformed cells and phagocytosis. SHIP-1 also serves as a scaffold for the recruitment of other proteins to the plasma membrane.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Peptide coresponding to a sequence within N-terminal domain of Human SHIP-1.
- Isotype:
- Mouse IgG2a
- Purification:
- Purified by protein-A affinity chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
