Anti-PKAc Monoclonal Antibody (Clone:6D2.1)
Product Sizes
0.1 mg
£551.00
30-1361-0.1MG
About this Product
- SKU:
- 30-1361
- translate.label.attr.clone:
- 6D2.1
- Clonality:
- Monoclonal
- Extra Details:
- Protein kinase A (PKA; cAMP-dependent protein kinase) is a key element of a ubiquitous signaling pathway important in the cell cycle; cellular communication; memory formation and behavior. PKA is composed of two catalytic (PKAc; Protein Kinase A catalytic subunit) and two regulatory subunits (PKAr). Upon binding cAMP; the complex dissociates to PKAr dimer and two activated PKAc ser/thr protein kinase catalytic monomers. The released PKAc can translocate into the nucleus and exert a regulatory role in the activation of multiple nuclear hormone receptors. However; PKAc-mediated activation of tonicity-dependent gene expression is cAMP independent. Humans express three types of PKAc subunit - PKAc alpha is present in most human tissues; PKAc beta and gamma are tissue-specific; the later is found in testes.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Peptide corresponding to amino acids ESPAQNTAHLDQFERIK of human proteinkinase A c alpha (PKAc alpha).
- Isotype:
- Mouse IgG1
- Purification:
- Purified by protein-A affinity chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
