Anti-CD24 Monoclonal Antibody (Clone:SN3)
Product Sizes
0.1 mg
£570.00
30-1353-0.1MG
About this Product
- SKU:
- 30-1353
- Additional Names:
- CD24||CD24A
- translate.label.attr.clone:
- SN3
- Clonality:
- Monoclonal
- Extra Details:
- CD24; also known as heat-stable antigen (HSA) or nectadorin; is a small mucin-like GPI-anchored extracellular membrane glycoprotein expressed on several cell types; including B cells. When B cells are activated and induced to further maturation; however; CD24 begins to disappear. CD24 seems to act as a gate-keeper for lipid rafts; thereby regulating the activity of integrins and other proteins such as the chemokine receptor CXCR4; it is also a ligand for P-selectin. CD24 triggering induces apoptosis of B cell precursors but not in mature resting B cells; where it instead inhibits their ability to proliferate in response to activation. CD24 expression is associated with invasiveness and poorer prognosis of carcinomas and is a marker of exosomes secreted into urine and amniotic fluid.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Glycoproteins purified from human NALM-1 cell line.
- Isotype:
- Mouse IgG1
- Purification:
- Purified by protein-A affinity chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
