Anti-CD105 / Endoglin Monoclonal Antibody (Clone:MEM-229)
Product Sizes
0.1 mg
£541.00
30-1313-0.1MG
About this Product
- SKU:
- 30-1313
- Additional Names:
- ENG||END
- translate.label.attr.clone:
- MEM-229
- Clonality:
- Monoclonal
- Conjugate:
- Unconjugated
- Extra Details:
- CD105 (Endoglin) is a homodimeric transmembrane glycoprotein serving in presence of TGFbetaR-2 as a receptor for TGFbeta-1 and TGFbeta-3. CD105 is highly expressed on endothelial cells and promotes angiogenesis during wound healing; infarcts and in a wide range of tumours and its gene expression is stimulated by hypoxia. CD105 prevents apoptosis in hypoxic endothelial cells and also antagonises the inhibitory effects of TGFbeta-1 on vascular endothelial cell growth and migration. Normal cellular levels of CD105 are required for formation of new blood vessels.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Recombinant Vaccinia virus containing the human CD105 (L-isoform) cDNA.
- Isotype:
- Mouse IgG2a
- Purification:
- Purified by protein-A affinity chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
