Anti-Clusterin / Apolipoprotein J Monoclonal Antibody (Clone:Hs-3)
Product Sizes
0.1 mg
£561.00
30-1290-0.1MG
About this Product
- SKU:
- 30-1290
- Additional Names:
- CLU||APOJ||CLI||KUB1||AAG4
- translate.label.attr.clone:
- Hs-3
- Clonality:
- Monoclonal
- Extra Details:
- Clusterin (APO J; SGP-2; TRPM-2; SP-40; pADHC-9; CLJ; T64; GP III; XIP8) is a 75-80 kD disulfide-linked heterodimeric protein containing about 30% of N-linked carbohydrate rich in sialic acid but truncated forms targeted to the nucleus have also been identified. It is a conserved secreted glycoprotein expressed by a wide range of tissues and being implicated in many physiological processes; including e.g. lipid transportation; complement inhibition; tissue remodeling; membrane recycling; or clearence of cellular debris. It is nearly ubiqitously expressed in most mammalian tissues and can be found in plasma; milk; urine; cerebrospinal fluid and semen. Clusterin is able to bind and form complexes with numerous partners (immunoglobulins; lipids; heparin; bacteria; complement components; paraoxonase; beta amyloid; leptin etc.) and is expressed in many pathological and clinically relevant situations including cancer; organ regeneration; infection; Alzheimer disease; retinitis pigmentosa; myocardial infarction; renal tubular damage; autoimmunity and others. A genuine function of clusterin is still enigmatic.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Freshly ejaculated human sperms were washed in PBS and extracted in 3% acetic acid; 10% glycerol; 30 mM benzaminidine. The acid extract was dialyzed against 0.2% acetic acid and subsequently used for immunization.
- Isotype:
- Mouse IgG1
- Purification:
- Purified by protein-A affinity chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
