Anti-Csk Monoclonal Antibody (Clone:CSK-04)
Product Sizes
0.1 ml
£581.00
30-1254-0.1ML
About this Product
- SKU:
- 30-1254
- Additional Names:
- CSK
- translate.label.attr.clone:
- CSK-04
- Clonality:
- Monoclonal
- Extra Details:
- C-terminal Src kinase (Csk) is a non-receptor protein tyrosine kinase which resembles Src-family kinases; but unlike them lacks the conserved autophosphorylation site; the regulatory C-terminal tyrosine as well as myristylation and palmitylation. Csk negatively regulates Src-family kinases by phosphorylation of their C-terminal regulatory tyrosine. Disruption of the csk gene causes constitutive activation of Src-family kinases; and overexpression of Csk usually counteracts their signaling. The Csk-mediated regulation of those Src-family kinases that are localized in lipid rafts is enabled by a ubiquitously expressed transmembrane adaptor PAG (also known as Cbp; Csk-binding protein); which recruits Csk.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Bacterially expressed recombinant fragment of human Csk corresponding to aa 330-450.
- Isotype:
- Mouse IgG1
- Purification:
- Purified by protein-A affinity chromatography
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
