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Antibodies

Anti-Fyn Monoclonal Antibody (Clone:FYN-01)

Product Sizes
0.1 mg
£581.00
30-1251-0.1MG
About this Product
SKU:
30-1251
Additional Names:
FYN
translate.label.attr.clone:
FYN-01
Clonality:
Monoclonal
Extra Details:
Fyn is a ubiquitously expressed Src-family protein tyrosine kinase with important roles e.g. in immune and nervous system. It regulates N-methyl-D-aspartate (NMDA) receptor functions; thus affecting various brain functions; and even many of its other substrates are important for neural migration; synaptic plasticity; oligodendrocyte differentiation; and axon growth and guidance. In immune system Fyn namely regulates the commitment of T cells to activation; is important in T cell anergy induction; promotes mast cell chemotaxis and reorganization of cytoskeleton and participates in mast cell activation. Fyn is also involved in embryonic stem cell growth and differentiation; associates with tubulin and may play roles in mitotic spindle formation.
Format:
Purified
Host:
Mouse
Immunogen:
Bacterially expressed recombinant fragment of human Fyn (aa 7-176).
Isotype:
Mouse IgG2b
Purification:
Purified by protein-A affinity chromatography
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 2-8[o]C. Do not freeze.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Figure 2: Immunofluorescence staining of Fyn in human primary fibroblasts using anti-Fyn (FYN-01; green). Actin cytoskeleton was decorated by phalloidin (red) and cell nuclei stained with DAPI (blue).
Figure 3: Immunofluorescence staining of Fyn in human HeLa cell line using anti-Fyn (FYN-01; green). Actin cytoskeleton was decorated by phalloidin (red) and cell nuclei stained with DAPI (blue). Fig. 4. Fig. 4. Immunofluorescence staining of Fyn in murine transformed fibroblasts using anti-Fyn (FYN-01; red). Actin cytoskeleton was decorated by phalloidin (green) and cell nuclei stained with DAPI (blue).
Figure 4: Immunofluorescence staining of Fyn in murine transformed fibroblasts using anti-Fyn (FYN-01; red). Actin cytoskeleton was decorated by phalloidin (green) and cell nuclei stained with DAPI (blue).
Figure 4: Immunofluorescence staining of Fyn in murine transformed fibroblasts using anti-Fyn (FYN-01; red). Actin cytoskeleton was decorated by phalloidin (green) and cell nuclei stained with DAPI (blue).