Anti-LAT Monoclonal Antibody (Clone:LAT-01)
Product Sizes
0.1 mg
£561.00
30-1236-0.1MG
About this Product
- SKU:
- 30-1236
- Additional Names:
- Linker for activation of T-cells family member 1; 36 kDa phospho-tyrosine adapter protein; p36-38
- translate.label.attr.clone:
- LAT-01
- Clonality:
- Monoclonal
- Extra Details:
- LAT (Linker for Activation of T cells) is a 36-38 kDa double-palmitoylated transmembrane adaptor protein expressed by T cells; pre-B cells; NK cells; mast cells and platelets. After immunoreceptor triggering; LAT becomes multiply tyrosine-phosphorylated by Syk-; Src-; or Tec-family kinases; providing docking sites for downstream signaling molecules. LAT is essential for TCR-dependent T cell- and FcepsilonRI-dependent mast cell activation; as well as for maturation of early thymocytes. It is also involved in NK cell signaling and platelet activation.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Bacterially produced recombinant polypeptide corresponding to the entire cytoplasmic domain of human LAT.
- Isotype:
- Mouse IgG1
- Purification:
- Purified by protein-A affinity chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
