Anti-Daxx / DAP6 Monoclonal Antibody (Clone:DAXX-01)
Product Sizes
0.1 mg
£551.00
30-1228-0.1MG
About this Product
- SKU:
- 30-1228
- Additional Names:
- DAXX||BING2||DAP6
- translate.label.attr.clone:
- DAXX-01
- Clonality:
- Monoclonal
- Extra Details:
- Daxx is an apoptosis-modulating death domain-associated protein with functions in transcriptional regulation. Daxx functions bot in cytoplasm; where it interacts with Fas; and in nucleus (residing in PML oncogenic domains); where it is involved in SUMO-dependent regulation of transcription and subnuclear compartmentalization. Daxx senzitizes the cells to apoptosis; but on the other hand; this protein may also serve in preventing apoptosis in the early embryo. Even regarding the transcription; Daxx can serve both as a corepressor and a coactivator. During ischemic stress; Daxx translocates from the nucleus to the cytoplasm; where in regulates sodium hydrogen exchanger isoform 1 (NHE1).
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Recombinant C-terminal part (aa 558-740) of human Daxx.
- Isotype:
- Mouse IgG1
- Purification:
- Purified by protein-A affinity chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
