Anti-SIT Monoclonal Antibody (Clone:SIT-01)
Product Sizes
0.1 mg
£561.00
30-1223-0.1MG
About this Product
- SKU:
- 30-1223
- Additional Names:
- SIT1||SIT
- translate.label.attr.clone:
- SIT-01
- Clonality:
- Monoclonal
- Extra Details:
- SIT (SHP2-interacting transmembrane adaptor protein) is expressed exclusively in lymphoid organs and acts either as a positive or as a negative regulatory element in T cell activation and in T cell development. Binding to Grb2 plays a pivotal role in signal transduction. Hubener et al. (2001) determined that the SIT gene contains 5 exons and spans 1.8 kb of genomic DNA. The SIT promoter demonstrated strong transcriptional activity and potential binding sites for both ubiquitous and lymphoid-specific transcription factors.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Bacterially produced recombinant intracellular fragment of human SIT.
- Isotype:
- Mouse IgG1
- Purification:
- Purified by protein-A affinity chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
