Anti-CD72 Monoclonal Antibody (Clone:3F3)
Product Sizes
0.1 mg
£532.00
30-1197-0.1MG
About this Product
- SKU:
- 30-1197
- Additional Names:
- CD72
- translate.label.attr.clone:
- 3F3
- Clonality:
- Monoclonal
- Extra Details:
- CD72 is a transmembrane glycoprotein expressed as a homodimer especially in B cells; but also in other antigen presenting cells such as dendritic cells and macrophages. Through one of its immunoreceptor tyrosine-based inhibitory motives (ITIMs); CD72 interacts with tyrosine phosphatase SHP-1; thereby suppressing B cell responsiveness. Binding of CD72 with its ligand CD100 (Sema4D) prevents BCR association and phosphorylation of CD72 and results in dissociation of SHP-1 from CD72; thus enables B cell activation.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Normal human lymphocytes from a lymph node.
- Isotype:
- Mouse IgG2b
- Purification:
- Purified by precipitation and chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
