Anti-CD27 Monoclonal Antibody (Clone:LT27)
Product Sizes
0.1 mg
£532.00
30-1195-0.1MG
About this Product
- SKU:
- 30-1195
- Additional Names:
- CD27||TNFRSF7
- translate.label.attr.clone:
- LT27
- Clonality:
- Monoclonal
- Extra Details:
- CD27 is a transmembrane 55 kDa protein of the nerve growth factor-receptor family; expressed as a disulfide-linked homodimer on mature thymocytes; peripheral blood T cells and a subpopulation of B cells. Activation of T cells via TCR-CD3 complex results in upregulation of CD27 expression on the plasma membrane as well as in the release of its soluble 28-32 kDa form; sCD27; detected in the plasma; urine or spinal fluid. This sCD27 is an important prognostic marker of acute and chronic B cell malignancies. RgpA; a cystein proteinase; although activating T cells through the protease-activated receptors (PARs); degradates CD27 and counteracts T cell activation mediated by CD27 and its ligand CD70.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Human peripheral blood lymphocytes
- Isotype:
- Mouse IgG2a
- Purification:
- Purified by precipitation and chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
