Alexa Fluor 700 conjugated Anti-CD34 / Mucosialin Monoclonal Antibody (Clone:4H11[APG])
Product Sizes
100 tests
£649.00
30-1185AF700-100TESTS
About this Product
- SKU:
- 30-1185AF700
- Additional Names:
- CD34;HLDA VI: WS Code M MA58
- translate.label.attr.clone:
- 4H11[APG]
- Clonality:
- Monoclonal
- Extra Details:
- CD34 is a highly glycosylated monomeric 111-115 kDa surface protein; which is present on many stem cell populations. It is a well established stem cell marker; though its expression on human hematopoietic stem cells is reversible. CD34 probably serves as a surface receptor that undergoes receptor-mediated endocytosis and regulates adhesion; differentiation and proliferation of hematopoietic stem cells and other progenitors. CD34 expression is likely to represent a specific state of hematopoietic development that may have altered adhering properties with expanding and differentiating capabilities in both in vitro and in vivo conditions. Specificity: The mouse monoclonal antibody 4H11[APG] reacts with extracellular class III epitope on CD34; a 110-115 kDa monomeric transmembrane phosphoglycoprotein expressed on hematopoietic progenitors cells and on the most pluripotential stem cells; it is gradually lost on progenitor cells. The antibody 4H11[APG] completely blocks binding of class III antibodies BIRMA K3 and 8G12 on KG1a cell line.
- Host:
- Mouse
- Immunogen:
- Permanent human cell line derived from peripheral leucocytes of a patient suffering from chronic myeloid leukaemia.
- Isotype:
- Mouse IgG1
- Purification:
- Purified antibody is conjugated with Alexa Fluor 700 NHS ester under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Protect from prolonged exposure to light. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
