Anti-CD273 / PD-L2 Monoclonal Antibody (Clone:24F.10C12) Biotin Conjugated
Product Sizes
0.1 mg
£581.00
30-1092-B-0.1MG
About this Product
- SKU:
- 30-1092-B
- Additional Names:
- PDCD1LG2||B7DC||CD273||PDCD1L2||PDL2
- translate.label.attr.clone:
- 24F.10C12
- Clonality:
- Monoclonal
- Conjugate:
- Biotin
- Extra Details:
- Specificity: The mouse monoclonal antibody 24F.10C12 recognizes an extracellular epitope of CD273 / PD-L2 (also known as B7-DC); a 25 kDa type I transmembrane protein expressed by dendritic cells; activated monocytes and T cells; heart; first trimester placenta; lung and liver; as well as in Hodgkin´s lymphoma cells and primary mediastinal B cell lymphoma (PMBL). Description: CD273 / PD-L2 (programmed death ligand-1); also known as B7-DC; is a member of the B7 family of regulatory proteins. It costimulates the proliferation of T cells; and mediates IFN gamma production. Ligation of CD273 on dendritic cells enhances dendritic cell activation and T cell responses. When interacting with CD279; it can act as a coinhibitor of the T cell function. CD273 expression is a useful marker to distinguish primary mediastinal B cell lymphoma from other diffuse large B cell lymphomas.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- human CD273 cDNA
- Isotype:
- Mouse IgG2a kappa
- Purification:
- Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:img1.jpg
