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Antibodies

Anti-CD193 / CCR3 Monoclonal Antibody (Clone:5E8) PE-Cy™5 conjugated

Product Sizes
100TESTS
£724.00
30-1080PE-Cy5-100TESTS
About this Product
SKU:
30-1080PE-Cy5
Additional Names:
CCR3||CMKBR3||CKR3||CKR-3
translate.label.attr.clone:
5 E 8
Clonality:
Monoclonal
Conjugate:
PE
Extra Details:
Specificity: The mouse monoclonal antibody 5E8 recognizes an extracellular epitope of CD193 (chemokine receptor 3); an approximately 41 kDa protein expressed above all in eosinophils and basophils. Description: CD193 / CCR3 is a G-protein coupled receptor for several chemokines; namely CCL11 (eotaxin); CCL26 (eotaxin-3); CCL7 (MCP-4); or CCL5 (RANTES). It is highly expressed on eosinophils and basophils; and is also detected in TH1 and TH2 cells; as well as in airway epithelial cells. CD193 is the key eosinophil chemokine receptor responsible for regulation of eosinophil migration and function. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1.
Host:
Mouse
Immunogen:
human CD193 transfectants
Isotype:
Mouse IgG2b kappa
Purification:
Purified antibody is conjugated with activated tandem dye of R-phycoerythrin-cyanine 5 (PE-Cy™5) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 2-8[o]C. Do not freeze.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
Figure 2: Separation of human CD193 positive CD45 dim basophils (red-filled) from CD193 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD193 (5E8) PE-Cy™5 antibody (concentration in sample 1μg/ml).
Figure 2: Separation of human CD193 positive CD45 dim basophils (red-filled) from CD193 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD193 (5E8) PE-Cy™5 antibody (concentration in sample 1μg/ml).