Anti-CD114 / G-CSFR Monoclonal Antibody (Clone:LMM741)
Product Sizes
0.1 mg
£532.00
30-1076-0.1MG
About this Product
- SKU:
- 30-1076
- Additional Names:
- CSF3R||GCSFR
- translate.label.attr.clone:
- LMM741
- Clonality:
- Monoclonal
- Extra Details:
- CD114 / G-CSFR (granulocyte colony-stimulating factor receptor; also known as CSF3R) is a type I transmembrane glycoprotein which upon binding of its ligand (G-CSF; granulocyte colony-stimulating factor) homodimerizes and activates signaling transduction to mediate cell proliferation; survival; and differentiation. It is expressed by granulocytes at all stages of their differentiation; as well as by monocytes; dendritic cells; and mature platelets. Among non-hematopoietic cells; it is expressed e.g. by endothelial cells; placenta; trophoblasts; and many tumor cell lines. This antigen is a target for stem cell mobilization for blood stem cell transplantation; for enhancing recovery of myelopoiesis following chemotherapy and in the treatment of patients with severe chronic neutropenia.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- CHO cells transfected with human CD114
- Isotype:
- Mouse IgG1
- Purification:
- Purified by protein-A affinity chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:30-1076.jpeg
