Anti-CD49b / Integrin alpha 2 Monoclonal Antibody (Clone:AK7)
Product Sizes
0.1 mg
£532.00
30-1071-0.1MG
About this Product
- SKU:
- 30-1071
- Additional Names:
- ITGA2||CD49B
- translate.label.attr.clone:
- AK7
- Clonality:
- Monoclonal
- Extra Details:
- CD49b / Integrin alpha 2 (ITGA2; alpha 2 subunit of VLA-2) heterodimerizes with CD29 to form the VLA-2 integrin alpha2/beta1 complex; which serves as a receptor for type I collagen; laminin; and E-cadherin. It also acts as a receptor for echovirus. Expressed on platelets; activated lymphocytes; monocytes; fibroblasts; epitelial and endothelial cells; CD49b mediates adhesion of these cells to the extracellular matrix. This interaction supports e.g. T cell proliferation and cytokine production; or wound healing. Defect in CD49b is associated with bleeding disorder platelet-type 9. Antibodies against CD49b are found in several immune disorders; including neonatal alloimmune thrombocytopenia.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Human platelets
- Isotype:
- Mouse IgG1
- Purification:
- Purified by protein-A affinity chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
