FITC Conjugated Anti-CD102 / ICAM-2 Monoclonal Antibody (Clone:CBR-IC2/2)
Product Sizes
100 tests
£581.00
30-1069F-100TESTS
About this Product
- SKU:
- 30-1069F
- Additional Names:
- ICAM2; CD102
- translate.label.attr.clone:
- CBR-IC2/2
- Clonality:
- Monoclonal
- Conjugate:
- FITC
- Extra Details:
- CD102 / ICAM-2 (intracellular cell adhesion molecule-2); a counter receptor of LFA-1 (CD11a/CD18); is a transmembrane glycoprotein with two extracellular IgC-like domains and intracellular C-terminal tail. It is involved in lymphocyte recirculation and homing to the sites of inflammation. Through interaction with integrins it provides to the immune cells costimulatory signals. Expression of CD102 on blood cells (lymphocytes; monocytes; thrombocytes) is lower than on endothelium and follicular dendritic cells. CD102 levels are upregulated in lymph nodes with malignant infiltration. Specificity: The mouse monoclonal antibody CBR-IC2/2 recognizes an extracellular epitope of CD102 (ICAM-2); an approximately 55 kDa type I transmembrane glycoprotein expressed mainly on vascular endothelial cells and folicular dendritic cells; in lower amount on lymphocytes; monocytes and platelets.
- Host:
- Mouse
- Immunogen:
- Human CD102 cDNA transfected COS cells
- Isotype:
- Mouse IgG2a
- Purification:
- Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Protect from prolonged exposure to light. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:30-1069F.jpg
