Anti-CD184 / CXCR4 Monoclonal Antibody (Clone:12G5)
Product Sizes
0.1 mg
£532.00
30-1067-0.1MG
About this Product
- SKU:
- 30-1067
- Additional Names:
- CXCR4
- translate.label.attr.clone:
- 12G5
- Clonality:
- Monoclonal
- Extra Details:
- CD184; also known as CXCR4 or fusin; is a receptor for the C-X-C chemokine SDF-1. It is expressed mainly in hematopoietic cells; vascular endothelium; and neural tissue. CD184 is a G-protein coupled receptor containing extracellular N-terminal; seven transmembrane domains and intracellular C-terminal domain. It transduces signal by increasing the intracellular calcium level. CD184 plays an essential role in vascularization of the gastrointestinal tract; and is involved in cerebellar development and in hematopoiesis. It is also a coreceptor (with CD4) for HIV-1 X4 virus and a primary receptor for some HIV-2 isolates.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- CP-MAC-infected Sup-T1 cells
- Isotype:
- Mouse IgG2a
- Purification:
- Purified by protein-A affinity chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
