Anti-CD40 Monoclonal Antibody (Clone:HI40a)-Azide free
Product Sizes
0.1 mg
£541.00
30-1017-0.1MG
About this Product
- SKU:
- 30-1017
- Additional Names:
- TNFRSF5
- translate.label.attr.clone:
- HI40a
- Clonality:
- Monoclonal
- Extra Details:
- CD40 is a costimulatory molecule of the TNF receptor superfamily and is expressed on many cell types; such as B cells; monocytes/macrophages; dendritic cells; endothelial cells; fibroblasts or vascular smooth muscle cells. Interaction of CD40 and its ligand CD154 (CD40L) is required for the generation of antibody responses to T-dependent antigens as well as for the development of germinal centers and memory B cells. In monocytes/macrophages CD40 engagement induces production of pro-inflammatory cytokines and chemokines. CD40-CD154 interactions are also critical for development of CD4 T cell-dependent effector functions. CD40 links innate and adaptive immune responses to bacterial stimuli and serves as an important regulator affecting functions of other costimulatory molecules.
- Format:
- Azide free
- Host:
- Mouse
- Immunogen:
- Human CD40a
- Isotype:
- Mouse IgG1
- Purification:
- Purified by protein-A affinity chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
