Recombinant TLR2 Protein with human Fc Tag
Product Sizes
25µg
£595.00
21-1019-25UG
About this Product
- SKU:
- 21-1019
- Extra Details:
- Source: CHO-K1. TLR2 belongs to the Toll-like receptor (TLR) family that plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) which are expressed on infectious agents; and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR2 is expressed most abundantly in peripheral blood leukocytes; and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB. TLR2 Human Recombinant produced in CHO-K1 cells is a single; glycosylated polypeptide chain containing 578 amino acids (19-588 aa) and having a molecular mass of 65.5kDa (Migrates at 50-70kDa on SDS-PAGE under reducing conditions).TLR2 is expressed with human Fc tag (27 kDa) at C-Terminus and purified by protein G column. Total size of the protein is approximately 100 kDa.
- Purification:
- >90% by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Recombinant TLR2-Fc Protein is shipped on ice packs. Upon arrival; Store at -20[o]C. Do not freeze-thaw multiple times.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:TLR2-Western 21-10019.jpg
