Recombinant Human ACE2 His and FLAG Tag
Product Sizes
50µg
£436.00
21-1016-50UG
100µg
£606.00
21-1016-100UG
500µg
£1926.00
21-1016-500UG
About this Product
- SKU:
- 21-1016
- Extra Details:
- Source: 293 HEK cells. Angiotensin-converting enzyme 2 (ACE2) is an ectoenzyme (carboxypeptidase) with an extracellular catalytic domain that predominantly localizes at the plasma membrane and is thereby able to hydrolyze circulating peptides. ACE2 has approximately 42% sequence identity with ACE; and its cytoplasmic and transmembrane domains show 48% homology to the protein collectrin that plays a critical role in the amino acid absorption of the kidney. ACE2 converts angiotensin I to angiotensin 1-9; a peptide of unknown function; and angiotensin II to angiotensin 1-7; a vasodilator. ACE2 is involved in the regulation of systemic blood pressure and has direct effects on cardiac functions. It is expressed predominantly in endothelial cells of the lung; gut; heart and kidney. ACE2 together with the protease TMPRSS2 acts as a functional receptor for SARS coronavirus as well as for the new highly pathogenic coronavirus; 2019-nCoV/SARS-CoV-2; which is the cause of COVID-19.
- Purification:
- >95% by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Recombinant Human ACE2 His Tag protein is shipped on ice packs. Upon arrival; Store at -20[o]C. Do not freeze-thaw multiple times.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
