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SARS-CoV-2 Spike S1 Mutant Sampler Set

Product Sizes
25 X 5µg
£876.00
21-1013-25X5UG
About this Product
SKU:
21-1013
Extra Details:
This SARS-CoV-2 Spike S1 Mutant Sampler Set contains: wild type Spike S1 protein (Cat. No. 21-1008); D614G mutant (Cat. No. 21-1009); N439K mutant (Cat. No. 21-1012); K417N/E484K/N501Y (South African) mutant (Cat. No. 21-1017); and S13l/W152C/L452R (Southern California) mutant (Cat. No. 21-1018) recombinant proteins expressed in CHO-K1. The spike protein S1 subunit of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) attaches the virus to its cellular receptor; angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S1 mediates this interaction. The S protein plays key parts in the induction of neutralizing antibodies and T-cell responses; as well as protective immunity.
Purification:
>95% by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
SARS-CoV-2 Spike S1 Mutant Sampler Set is shipped on ice packs. Upon arrival; store at -20[o]C. Do not freeze-thaw multiple times.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
Figure-2: Comparative binding of Spike S1 variants to sACE2: Wells of a 96-well microtiter plate were coated with 100 ng in duplicates each of S1-WT (Cat# 21-1008); S1-N439K (Cat# 21-1012); S1-D614G (Cat# 21-1009); S1-South Africa (Cat# 21- 1017); and S1-Southern California (Cat# 21-1018). Binding to sACE2 was determined by adding different concentrations of biotinylated-sACE2 (Cat# 21-1006).
Figure-2: Comparative binding of Spike S1 variants to sACE2: Wells of a 96-well microtiter plate were coated with 100 ng in duplicates each of S1-WT (Cat# 21-1008); S1-N439K (Cat# 21-1012); S1-D614G (Cat# 21-1009); S1-South Africa (Cat# 21- 1017); and S1-Southern California (Cat# 21-1018). Binding to sACE2 was determined by adding different concentrations of biotinylated-sACE2 (Cat# 21-1006).