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SARS CoV2 Spike S1 C-Term His Tag Protein

Product Sizes
50µg
£436.00
21-1008-50UG
100µg
£606.00
21-1008-100UG
500µg
£1926.00
21-1008-500UG
About this Product
SKU:
21-1008
Extra Details:
Source: Covid 19 Spike S1-His in CHO-K1.The spike protein (S1) of coronavirus (CoV2) attaches the virus to its cellular receptor; angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses; as well as protective immunity.
Purification:
greater than 95% by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
SARS-CoV-2 Spike S1-His Protein is shipped on ice packs. Upon arrival; Store at -20[o]C. Do not freeze-thaw multiple times.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg
Figure 2: Binding assay of recombinant SARS CoV-2 Spike S1 C-Term His Tag Protein (Cat. No. 21-1008) with recombinant Human ACE2 Fc Protein (Cat No. 21-1007). An ELISA plate was coated with 1µg/ml of recombinant SARS CoV-2 Spike S1 C-Term His Tag Protein; and the plate was incubated overnight at 4oC. Different concentrations (100 ng/well to 0 ng/well) of recombinant Human ACE2 Fc Protein was added to the wells. HRP conjugated goat anti-human Fc was used as secondary antibody.
Figure 3: Comparative binding of Spike S1 variants to sACE2: Wells of a 96-well microtiter plate were coated with 100 ng in duplicates each of S1-WT (Cat# 21-1008); S1-N439K (Cat# 21-1012); S1-D614G (Cat# 21-1009); S1-South Africa (Cat# 21-1017); and S1-Southern California (Cat# 21-1018). Binding to sACE2 was determined by adding different concentrations of biotinylated-sACE2 (Cat# 21-1006).
Figure 3: Comparative binding of Spike S1 variants to sACE2: Wells of a 96-well microtiter plate were coated with 100 ng in duplicates each of S1-WT (Cat# 21-1008); S1-N439K (Cat# 21-1012); S1-D614G (Cat# 21-1009); S1-South Africa (Cat# 21-1017); and S1-Southern California (Cat# 21-1018). Binding to sACE2 was determined by adding different concentrations of biotinylated-sACE2 (Cat# 21-1006).