Human CD80 Recombinant Fc fusion Protein (Active) Biotin Conjugated
Product Sizes
100µg
£551.00
21-1002-B-100UG
About this Product
- SKU:
- 21-1002-B
- Additional Names:
- T-lymphocyte activation antigen CD80; Activation B7-1 antigen; BB1; CTLA-4 counter-receptor B7.1; B7; CD28LG; CD28LG1; LAB7
- Extra Details:
- The B-lymphocyte activation antigen B7-1 (referred to as B7); also known as CD80; is a member of cell surface immunoglobulin superfamily and is expressed on the surface of antigen-presenting cells including activated B cells; macrophages and dendritic cells. As costimulatory ligands; B7-1 which exists predominantly as dimer and the related protein B7-2; interact with the costimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells; and thus constitute one of the dominant pathways that regulate T cell activation and tolerance; cytokine production; and the generation of CTL. The B7/CD28/CTLA4 pathway has the ability to both positively and negatively regulate immune responses. CD80 is thus regarded as promising therapeutic targets for autoimmune diseases and various carcinomas. Cancer Immunotherapy Co- inhibitory Immune Checkpoint Targets Immune Checkpoint Immune Checkpoint Detection Human extracellular domain CD80 (B7-1) Fc fusion protein. This protein is expressed in CHO-K1 cells and purified using protein G colomn. Protein MW 53 kDa but SDS it runs arround 65 kDa due to glycosylation.
- Purification:
- 95% Purity SDS-PAGE and HPLC
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store it under sterile conditions at -20[o]C to -80[o]C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:CD80 Coom widecrop.jpg
