Human PD-L1 Recombinant Fc fusion Protein (Active) Biotin conjugated
Product Sizes
100µg
£551.00
21-1001-B-100UG
About this Product
- SKU:
- 21-1001-B
- Additional Names:
- B7 homolog 1; CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
- Extra Details:
- Host: CHO-K1 celline. PD-L1 (CD274/B7-H1) is a critical membrane-bound costimulatory molecule belongs to the B7 superfamily that inhibits immune responses through its receptor; PD-1 and PD-L1 play a key role in the pathogenesis of inflammatory diseases (programmed death 1). It is widely expressed in the mononuclear phagocyte system (MPS); may co-stimulate T cells and regulates inflammatory responses. PD-L1 exerts inflammation regulatory functions via a negative co-stimulatory effect on T cell functions to inhibit cytokine secretion; facilitate apoptosis of activated T cells and induce T cell anergy. Aberrant expression and dysregulation of CD274 have been reported during bacterial infection; inflammation and in numerous autoimmune diseases.
- Purification:
- 99% Purity SDS -PAGE and HPLC.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store it under sterile conditions at -4[o]C. It is recommended that the protein be aliquoted for optimal storage.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
