Polyclonal antibody to BAG3
Product Sizes
50 µl
£396.00
20-1117-50UL
About this Product
- SKU:
- 20-1117
- Additional Names:
- BAG3||BIS
- Clonality:
- Polyclonal
- Extra Details:
- The BAG proteins are a family of chaperone regulators that modulate a number of diverse processes including proliferation; survival; stress responses; tumorigenesis; neuronal differentiation; growth arrest and apoptosis (reviewed Takayama and Reed; 2001; Doong et al; 2002; and Doukhanina et al. 2006). BAG proteins have been characterized as co-chaperones and interact with the chaperone heat shock proteins 70; both constitutive Hsc70 and inducible Hsp70. BAG proteins bind through their BAG domain to the ATPase domain of Hsc70/Hsp70; and can modulate either positively or negatively the functions of the Hsc70/Hsp70 chaperone proteins. The BAG domain has been shown to contribute to the anti-apoptotic activity of BAG- family proteins. The anti-apoptotic activities of BAG-family proteins may be dependent on their interactions with Hsc70/Asp70 and/or binding to Bcl-2. In addition to the conserved BAG domain; BAG-family proteins also contain additional domains which enable them to interact with specific target proteins or to target them to specific locations within cells.
- Format:
- Sera
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide of human BAG-3 (amino acids 276-294 REGSPARSSTPLHSPSPIR) was used as immunogen for this antibody
- Isotype:
- Rabbit IgG
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
