Polyclonal antibody to TRAF-6
Product Sizes
50 µl
£396.00
20-1102-50UL
About this Product
- SKU:
- 20-1102
- Additional Names:
- TRAF6||RNF85
- Clonality:
- Polyclonal
- Extra Details:
- Human TRAF6 is a 522 amino acid protein. The TRAF (TNF receptor-associated factor) family is a group of adapter proteins (TRAFs 1-6) that link a wide variety of cell surface receptors to diverse signaling cascades leading to the activation of NF-kB and mitogen-activated protein kinases. TRAFs are major signal transducers for both the TNF and IL- 1/TLR receptor superfamilies and collectively play important functions in both adaptive and innate immunity. The carboxy-terminal region of TRAFs is required for self-association and interaction with receptor cytoplasmic domains following ligand-induced oligomerization. TRAFs interact with a variety of proteins that regulate receptor-induced cell death or survival; and TRAF-mediated signaling can promote cell survival or interfere with death receptor-induced apoptosis.
- Format:
- Sera
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide of human TRAF-6 (amino acids 451-469 DAKPELLAFQRPTIPRNPK) was used as immunogen for this antibody
- Isotype:
- Rabbit IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
