Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Antibodies

Polyclonal antibody to TRAF-4

Product Sizes
50 µl
£396.00
20-1100-50UL
About this Product
SKU:
20-1100
Additional Names:
TRAF4||CART1||MLN62||RNF83
Clonality:
Polyclonal
Extra Details:
This antibody recognizes TRAF4. Human TRAF4 is a 470 amino acid protein. The TRAF (TNF receptor-associated factor) family is a group of adapter proteins (TRAFs 1-6) that link a wide variety of cell surface receptors to diverse signaling cascades leading to the activation of NF-kB and mitogen-activated protein kinases. TRAFs are major signal transducers for both the TNF and IL- 1/TLR receptor superfamilies and collectively play important functions in both adaptive and innate immunity. The carboxy-terminal region of TRAFs is required for self-association and interaction with receptor cytoplasmic domains following ligand-induced oligomerization. TRAFs interact with a variety of proteins that regulate receptor-induced cell death or survival; and TRAF-mediated signaling can promote cell survival or interfere with death receptor-induced apoptosis.
Format:
Sera
Host:
Rabbit
Immunogen:
A synthetic peptide human TRAF-4 (amino acids 1-17 MPGFDYKFLEKPKRRLL) was used as immunogen for this antibody
Isotype:
Rabbit IgG
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
Supplier:
Abeomics
Type:
Antibodies:Polyclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Fig:2 Immunohistochemistry of formalin-fixed; paraffin embedded; normal human mammary epithelial tissue using the 20-1100 TRAF4 antibody. A-C: Strong TRAF4 staining is seen in the luminal epithelial cells of the interlobular terminal ducts (acini). However; there is absence of TRAF4 immunostaining in the myoepithelial cells along the basement membrane. B and C: higher magnifications of A. Data courtesy of Krajewska et al.
Fig:2 Immunohistochemistry of formalin-fixed; paraffin embedded; normal human mammary epithelial tissue using the 20-1100 TRAF4 antibody. A-C: Strong TRAF4 staining is seen in the luminal epithelial cells of the interlobular terminal ducts (acini). However; there is absence of TRAF4 immunostaining in the myoepithelial cells along the basement membrane. B and C: higher magnifications of A. Data courtesy of Krajewska et al.