Polyclonal antibody to TRAF-3
Product Sizes
50 µl
£396.00
20-1099-50UL
About this Product
- SKU:
- 20-1099
- Additional Names:
- TRAF3||CAP1||CRAF1
- Clonality:
- Polyclonal
- Extra Details:
- This antibody recognizes TRAF3. Human TRAF3 is a member of the; TRAF (TNF Receptor Associated Factor) protein family; having an approximate molecular weight of 568 amino acid.TRAF3 is a CD40 binding protein that contains a RING finger DNA binding motif and Cys/His rich region and coiled COIL domain. Like TRAF1 (TNF Receptor Associated Factor-1) and TRAF2 (TNF Receptor Associated Factor-2); it contains a C-terminal TRAF domain and has an apparent molecular mass of 64 kDa.TRAF3 is involved in mediating the signal transduction of CD40; a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the; LtBetaR (Lymphotoxin-Beta Receptor) signaling complex; which induces NF-KappaB activation and cell death initiated by LT-Beta (Lymphotoxin-Beta) ligation.
- Format:
- Sera
- Host:
- Rabbit
- Immunogen:
- A recombinant protein fragment of the cytoplasmic end of human TRAF-3 (amino acids 341-568) was used as immunogen for this antibody
- Isotype:
- Rabbit IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
