Polyclonal antibody to Semenogelin II
Product Sizes
50 µl
£396.00
20-1085-50UL
About this Product
- SKU:
- 20-1085
- Additional Names:
- SEMG2
- Clonality:
- Polyclonal
- Extra Details:
- Semenogelin I (SgI) and Semenogelin II (SgII) are the major seminal vesicle secreted proteins in human semen. SgI and SgII; in semen both originate from the glandular epithelium of the seminal vesicles which secrete them at high concentrations. Human Sg1 is a non-glycosylated protein of 439 amino acids with a molecular weight of ~50 kDa. A few percent of the worlds population also carry an allele that gives rise to a truncated SgI molecule with a molecular mass of 43 kDa. Human SgII is a 559 amino acid protein with a molecular weight of approx 63 kDa. SgII has a potential site for N-linked glycosylation and approximately half of the molecules in human semen are glycosylated yielding two SgII species with a different of 5 kDa. SgI has a single Cys residue and SgII has two Cys residues; and the molecules can exist as covalent homo- and heteromultimers. Whereas SgI/SgII was originally identified as the major components present in seminal vesicle secretion; they are now known to be expressed in a number of tissues. The list includes seminal vesicles; epididymis; vas deferens; prostate; skeletal muscle; kidney; colon; trachea; lung; breast and retina as well as in several malignant tissues and cell lines. The non-genital expression of SgI/SgII suggests that these proteins also have functions that are unrelated to sperm.
- Format:
- Sera
- Host:
- Rabbit
- Immunogen:
- Gel purified rat p42 seminal vesicle protein II from rodent seminal vesicle secretion fluid (corresponding to secreted Semenogelin II) was used as immunogen for this antibody
- Isotype:
- Rabbit IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
