Polyclonal antibody to NOD1
Product Sizes
50 µl
£396.00
20-1075-50UL
About this Product
- SKU:
- 20-1075
- Additional Names:
- NOD1||CARD4
- Clonality:
- Polyclonal
- Extra Details:
- This antibody recognizes NOD1 (CARD4). Human NOD1 (CARD4) is a 953 amino acid protein. NOD (nucleotide-binding oligomerization domain) proteins are a family of cytosolic proteins which have been implicated in innate recognition of bacteria; the induction of inflammatory responses; and the regulation of caspase activation and apoptosis. NOD1/CARD4 (caspase-recruitment domain 4 gene) is a PRM that recognizes specific peptidoglycan (PGN) components of bacterial cell walls. NOD1 is expressed by cell types that are exposed to PGN under physiological conditions including antigen-presenting cells (APCs) such as macrophages and dendritic cells; and epithelial cells (reviewed in Strober et al. 2006). NOD1 is thought to play a role in the pathogenesis of human gastrointestinal disease and is associated with inflammatory bowel diseases and asthma. It is involved in host defense against Helicobacter pylori infection of the gastric mucosa; a chronic infection that can lead to peptic ulcers and gastric cancer.
- Format:
- Sera
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide of human NOD1 (amino acids 494-512 QLGFLRALPELGPGGDQQS) was used as immunogen for this antibody
- Isotype:
- Rabbit IgG
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
