Polyclonal antibody to Cre
Product Sizes
50 µl
£396.00
20-1058-50UL
About this Product
- SKU:
- 20-1058
- Additional Names:
- Recombinase cre
- Clonality:
- Polyclonal
- Extra Details:
- This antibody recognizes the recombinase protein; CRE. CRE is a 343 amino acid protein. The Cre enzyme; belongs to a member of a large family of recombinases; recognizes loxP which is a sequence motif of 34 bp from the PI bateriophage. Cre and lox comprise the Cre/lox system which was first developed in the late 1980 to artificially manipulate gene expression. As an example; mice with the Cre protein expressing in a specific cell type are bred with mice that contain a target gene surrounded by loxP sites. When the mice are bred; the cells carrying Cre will cause those cells to lose the target gene. If the Cre gene is; for example; bound to a promoter that only allows Cre production in neuronal cells; the target gene will be deleted only in those cells. This has led to its application in many experiments; for example in selectively labeling neuronal cells in the brain thereby differentiating them from other types of surrounding cells.
- Format:
- Sera
- Host:
- Rabbit
- Immunogen:
- A synthethic peptide of Cre protein (amino acids 2-11 SNLLTVHQNL) of the bacteriophage was used as immunogen for this antibody
- Isotype:
- Rabbit IgG
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
