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Proteins and Peptides

Lipopolysaccharide-LPS from Ecoli 0111:B4; Ion-Exchange Chromatography;TLR4 ligand

Product Sizes
1 mg
£232.00
15-1030-1MG
5 mg
£661.00
15-1030-5MG
About this Product
SKU:
15-1030
Extra Details:
Lipopolysaccharides (LPSs) are characteristic components of the cell wall of Gram-negative bacteria. LPS and its lipid A moiety stimulate cells of the innate immune system by the Toll-like receptor 4 (TLR4); a member of the Toll-like receptor protein family; which recognizes common pathogen-associated molecular-patterns (PAMPs). Lipopolysaccharides (LPS) are localized in the outer layer of the membrane and are; in noncapsulated strains; exposed on the cell surface. They contribute to the integrity of the outer membrane; and protect the cell against the action of bile salts and lipophilic antibiotics.
Purification:
Ion-Exchange Chromatography; purity 99.9%
Shipping Conditions:
Blue Ice
Storage Conditions:
Stable for at least 2 years after receipt when stored at 4[o]C. Do not freeze the item.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules:Toxins
Fig-1: Induction of TNF-alpha promoter activity mediated by LPS-stimulated TLR4. TNF-alpha Leeporter™ Luciferase Reporter-RAW264.7 Cells (Abeomics; Cat. No. 14-106ACL) were treated with different concentrations of LPS (15-1030) for 16 h; and then luciferase activity was measured.