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TLR3/NF-kB Leeporter™ GFP Reporter-HEK293 Cell Line

Product Sizes
1 Vial
£5394.00
14-701ACL-1VIAL
About this Product
SKU:
14-701ACL
Extra Details:
The TLR3/NF-kB Leeporter™ GFP Reporter cell line is a stably transfected HEK293 cell line; which expresses full-length human Toll-like receptor 3 (TLR3) and enhanced green fluorescent protein (eGFP) reporter gene under the transcriptional control of the NF-kB response element. Functional activity of the cell line has been validated by TLR3 ligand assay; in which upon activation by poly (I:C); TLR3 quickly initiates TRIF-dependent signaling pathway and mediates nuclear translocation of NF-kB (Figures 1 and 2).
Shipping Conditions:
Blue Ice
Storage Conditions:
Immediately upon receipt; store in liquid nitrogen.
Supplier:
Abeomics
Type:
Cells:Cell Lines
Fig-2: Induction of TLR3 activity by Poly(I:C) in TLR3/NF-kB Leeporter™ GFP reporter™HEK293 cells was analyzed by flow cytometry. Poly(I:C) was treated at 0.01; 0.05; 0.1; 0.5; 2.5 and 25 ug/ml as noted. Vehicle control (Black line; empty); Poly(I:C) treatment (Green line; grey-filled).
Fig-2: Induction of TLR3 activity by Poly(I:C) in TLR3/NF-kB Leeporter™ GFP reporter™HEK293 cells was analyzed by flow cytometry. Poly(I:C) was treated at 0.01; 0.05; 0.1; 0.5; 2.5 and 25 ug/ml as noted. Vehicle control (Black line; empty); Poly(I:C) treatment (Green line; grey-filled).