TLR3/HEK293 Stable Cell Line
Product Sizes
1 Vial
£2747.00
14-532ACL-1VIAL
About this Product
- SKU:
- 14-532ACL
- Extra Details:
- TLR3/HEK293 Stable Cell Line is a stably transfected HEK293 cell line which expresses human Toll-like receptor 3 (TLR3; also designated as CD283). TLR3 is known to localize in the endosomal compartment and mediates immune responses by recognition of double-stranded RNAs in endosomes; which leads to up-regulation of the interferon-alpha/beta and induction of antiviral protein synthesis activity. Note that TLR3 in the TLR3/HEK293 stable cell line contains the N-terminal HA tag (Figure 2); which does not interfere with TLR3 activity as confirmed by functional assay (Figure 1). Sequence data: Human TLR3 (accession number NP_003256) MRQTLPCIYFWGGLLPFGMLCASSTTKCTVSHEVADCSHLKLTQ VPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLK VLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFH AIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNL TMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFT KQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS LRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQ EWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHI LNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS VEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPH YHGFPVRLFDTSSCKDSAPFELFFMINTSILLIFIFIVLLIHFEGWRISFYWNVSVHR VLGFKEIDRQTEQFEYAAYIIHAYKDKDWVWEHFSSMEKEDQSLKFCLEERDFEAGVF ELEAIVNSIKRSRKIIFVITHHLLKDPLCKRFKVHHAVQQAIEQNLDSIILVFLEEIP DYKLNHALCLRRGMFKSHCILNWPVQKERIGAFRHKLQVALGSKNSVH
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Immediately upon receipt; store in liquid nitrogen.
- Supplier:
- Abeomics
- Type:
- Cells:Cell Lines
- Manufacturer's Data Sheet:14-532ACL_HEK-TLR3_F1.png
