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NFAT Leeporterâ„¢ Luciferase Reporter-Jurkat Cell Line

Product Sizes
1 Vial
£1881.00
14-150ACL-1VIAL
About this Product
SKU:
14-150ACL
Extra Details:
The NFAT Leeporterâ„¢ Luciferase Reporter cell line is a stably transfected Jurkat T cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the Nuclear Factor of Activated T-cells (NFAT) response element; so that the cell line is designed to measure the transcriptional activity of NFAT. NFAT is a transcription factor originally found in activated T lymphocytes; and is now known to regulate not only T cell activation and differentiation but also the function of other immune cells including dendritic cells; B cells and megakaryocytes. The NFAT induction by anti-CD3 antibody and ionomycin is shown in Figures 1 through 4.
Shipping Conditions:
Blue Ice
Storage Conditions:
Immediately upon receipt; store in liquid nitrogen.
Supplier:
Abeomics
Type:
Cells:Cell Lines
Fig-2: EC50 evaluation of anti-CD3 antibody against NFAT induction in NFAT Leeporterâ„¢ - Jurkat T cells.
Fig-3: Induction of NF-kB activity by Ionomycin in the presence of PMA in NFAT Leeporterâ„¢ - Jurkat T cells.
Fig-4: Induction of NF-kB activity by Ionomycin in the absence of PMA in NFAT Leeporterâ„¢ - Jurkat T cells.
Fig-4: Induction of NF-kB activity by Ionomycin in the absence of PMA in NFAT Leeporterâ„¢ - Jurkat T cells.