STAT3 Leeporter™ Luciferase Reporter-HEK293 Cell Line
Product Sizes
1 Vial
£4481.00
14-114ACL-1VIAL
About this Product
- SKU:
- 14-114ACL
- Extra Details:
- The STAT3 Leeporter™ Luciferase Reporter cell line is a stably transfected HEK 293 cell line which expresses Renilla luciferase reporter under the transcriptional control of the STAT3 responsive promoter; so that the cell line is designed to measure the transcriptional activity of STAT3. As a transcription factor; Signal Transducer and Activator of Transcription 3 (STAT3) is activated through phosphorylation at tyrosine 705 in response to various cytokines including IL-6; interferons; epidermal growth factor; hepatocyte growth factor and leukemia inhibitory factor. The phosphorylated STAT3 forms homodimers or heterodimers with STAT1; and the dimers translocate to nucleus in which DNA binding/promoter induction occurs. The STAT3 induction by IL-6 as well as Oncostatin-M is shown in Figures 1 and 3.
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- Immediately upon receipt; store in liquid nitrogen.
- Supplier:
- Abeomics
- Type:
- Cells:Cell Lines
- Manufacturer's Data Sheet:14-114ACL_STAT3_HEK293_Fig1new.png
