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GATA3 Leeporter™ Luciferase Reporter-HEK293 Cell Line

Product Sizes
1 Vial
£1931.00
14-109ACL-1VIAL
About this Product
SKU:
14-109ACL
Extra Details:
The GATA3 Leeporter™ Luciferase Reporter cell line is a stably transfected HEK 293 cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the GATA3 response element; so that the cell line is designed to measure the transcriptional activity of GATA3. As a zinc-finger transcription factor; GATA3 (GATA-binding protein 3) plays a critical role in early and late T cell differentiation; which regulates Th1/Th2 differentiation. GATA3 has been shown to induce Th2 differentiation and repress Th1 differentiation. GATA3 is also known to promote the secretion of IL-4; IL-5 and IL-13 from Th2 cells. The GATA3 induction by phorbol 12-myristate 13-acetate (PMA)  is shown in Figure 1.
Shipping Conditions:
Dry Ice
Storage Conditions:
Immediately upon receipt; store in liquid nitrogen.
Supplier:
Abeomics
Type:
Cells:Cell Lines